A glandular trichome-specific monoterpene alcohol dehydrogenase from Artemisia annua
نویسندگان
چکیده
منابع مشابه
Investigation of Glandular Trichome Proteins in Artemisia annua L. Using Comparative Proteomics
Glandular secreting trichomes (GSTs) are called biofactories because they are active in synthesizing, storing and secreting various types of plant secondary metabolites. As the most effective drug against malaria, artemisinin, a sesquiterpene lactone is derived from GSTs of Artemisia annua. However, low artemisinin content (0.001%~1.54% of dry weight) has hindered its wide application. We inves...
متن کاملProteomic analysis of the medicinal plant Artemisia annua: Data from leaf and trichome extracts
This article contains raw and processed data related to research published by Bryant et al.[1]. Data was obtained by MS-based proteomics, analysing trichome-enriched, trichome-depleted and whole leaf samples taken from the medicinal plant Artemisia annua and searching the acquired MS/MS data against a recently published contig database [2] and other genomic and proteomic sequence databases for ...
متن کاملIsolation and Characterization of Three New Monoterpene Synthases from Artemisia annua
Artemisia annua, an annual herb used in traditional Chinese medicine, produces a wealth of monoterpenes and sesquiterpenes, including the well-known sesquiterpene lactone artemisinin, an active ingredient in the treatment for malaria. Here we report three new monoterpene synthases of A. annua. From a glandular trichome cDNA library, monoterpene synthases of AaTPS2, AaTPS5, and AaTPS6, were isol...
متن کاملArtemisia annua L
Shoot cultures of Artemisia annua L. were cultivated in three different micropropagation systems: an ultrasonic nutrient mist bioreactor (UNMB), a modified ultrasonic nutrient mist bioreactor (MUNMB) and solid culture in Magenta boxes. The shoots cultivated in the UNMB and MUNMB showed excellent growth. The dry weight increase (35 times) of shoot cultures in the MUNMB was higher than those (25 ...
متن کاملThe molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua.
At some point during biosynthesis of the antimalarial artemisinin in glandular trichomes of Artemisia annua, the Delta11(13) double bond originating in amorpha-4,11-diene is reduced. This is thought to occur in artemisinic aldehyde, but other intermediates have been suggested. In an effort to understand double bond reduction in artemisinin biosynthesis, extracts of A. annua flower buds were inv...
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ژورنال
عنوان ژورنال: Phytochemistry
سال: 2010
ISSN: 0031-9422
DOI: 10.1016/j.phytochem.2010.04.026